QUANTIFICATION OF HUMAN COLON ENS USING NOVEL OPTICAL CLEARING METHODS AND 3-DIMENTIONAL IMAGING. Kahleb Graham1, Silvia Huerta Lopez1, Archana Shenoy2, Rajarshi Sengupta3, Michael Feldman4, Emma Furth4, Federico Valdivieso4, Amanda Lemke1, Benjamin Wilkins5, Pierre Russo5, Edward Doolin6, Robert Heuckeroth1,7. 1Gastroenterology , Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; 2Pathology and Laboratory Medicine, University of Florida , Gainesville, FL, USA; 3American Association for Cancer Research, Philadelphia, PA, USA; 4Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; 5Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; 6Pediatric and Thoracic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; 7Pediatrics , Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.