2:30 PM - 4:00 PM - Concurrent Session II
What to Do when You Get stuck: An Interdisciplinary Panel Discussion of Challenging Constipation Cases
Moderators: Lusine Ambartsumyan, MD, Seattle Children's Hospital and Rodrigo Vazquez Frias, Md, MsC, PhD, Hospital Infantil De México Federico Gómez
Panel:
- Alexandra Kilgore, MD, Children's Hospital Colorado
- Christina Low Kapalu, PhD, Oregon Health Science University
- Richard J. Wood, MD, Nationwide Children's Hospital
- Toni Solari, RD, LDN, Boston Children's Hospital
Learning objectives:
- Discuss the role of diet in pediatric functional constipation
- Identify barriers to treatment and the behavioral interventions necessary to implement effective treatment strategies in pediatric functional constipation
- Review the medical management of pediatric functional constipation and therapy escalation in refractory constipation
- Recognize the utility of diagnostic testing in the evaluation of refractory constipation
- Understand the role of surgery in the management of pediatric refractory constipation
It Takes a Village: Addressing Liver Disease Together
Moderators: Pamela Valentino, MD, Seattle Children's Hospital and Sara Hassan, MD, University of Texas Southwestern (UTSW)
2:30 PM Fontan-Associated Liver Disease: Physiology and the Fight Against Progression
Ryan Fischer, MD, Children's Mercy Kansas City
Learning objectives:
- Introduce Fontan-associated liver disease (FALD)
- Understand pathophysiology behind development
- Delineate best practices for monitoring
- Discuss potential to ameliorate progression
2:55 PM
Flash Abstracts
- METABOLOMIC PROFILING IN GROWTH IMPAIRED PEDIATRIC LIVER TRANSPLANT RECIPIENTS
Luis Lopez, MD, Northwestern University Feinberg School of Medicine
- CHARACTERISTICS AND OUTCOMES OF FONTAN ASSOCIATED LIVER DISEASE IN CHILDREN FROM A MULTICENTER - INITIAL ANALYSIS OF 8 CENTERS IN USA
Chaowapong Jarasvaraparn, MD, Riley Hospital for Children at Indiana University Health
- MITOCHONDRIAL DNA CONTENT IN PERIPHERAL BLOOD CELLS AS A MARKER OF DISEASE PROGRESSION IN PEDIATRIC METABOLIC DYSFUNCTION ASSOCIATED STEATOTIC LIVER DISEASE (MASLD)
Joseph Chapman, MD, Children's Hospital at Montefiore
3:07 PM Balancing Hormonal Therapy and Liver Health in Adolescents with Chronic Liver Disease:
A Combined Medical and Psychological Approach
Jean Molleston, MD, Riley Hospital for Children and Jamie L. Ryan, PhD, Children's
Mercy Kansas City
Learning objectives:
- Delineate pathophysiologic considerations in decision-making regarding birth control and hormonal therapy in patients with liver disease or liver tumors
- Discuss risks and benefits of hormonal therapy with teenagers with chronic liver disease, transplant, or tumors
- Explain the role and impact of shared decision-making on self-management in adolescents with chronic illness
- Describe potential barriers and facilitators of shared decision-making in the context of hormonal therapy in adolescent liver disease
3:32 PM
Fellow Research Award
PEDIATRIC LIVER TRANSPLANT OUTCOMES AND THE ASSOCIATION WITH SOCIOECONOMIC
STATUS: A POPULATION-BASED COHORT STUDY OVER 30 YEARS
Toshifumi Yodoshi, MD, PhD, The Hospital for Sick Children
Cutting to the Core: Balancing Medicine Vs Surgery in Pediatric IBD
Moderators: Sabina Ali, MD, UCSF Benioff Children's Hospital and Shervin Rabizadeh, MD, Cedars-Sinai
2:30 PM OUTCOMES OF VEDOLIZUMAB THERAPY IN BIO-NAIVE VERSUS BIO-EXPOSED
CHILDREN WITH INFLAMMATORY BOWEL DISEASE
Casey Konys, MD, Ann & Robert H Lurie Children's Hospital of Chicago
2:37 PM NATIONAL TRENDS IN COLECTOMY RATES IN PEDIATRIC PATIENTS WITH ULCERATIVE
COLITIS AND IBD-UNCLASSIFIED IN THE PRE AND POST BIOLOGIC ERA
Emily Lai, MD, University of California San Francisco
2:44 PM One Patient, Many Perspectives: Multidisciplinary Insights - Medicine Vs Surgery in IBD
Panel:
- Jennifer Dotson, MD, MPH, Arkansas Children's Hospital
- Jennifer Strople, MD, Ann & Robert H. Lurie Children's Hospital
- Lisa McMahon, MD, FACS, FAAP, Phoenix Children's Hospital
- Jennie David, PhD, Nationwide Children's Hospital
Learning objectives:
- Differentiate medical and surgical indications in pediatric IBD
- Recognize when medical management may be optimized or exhausted, and when surgical intervention becomes necessary
- Evaluate multidisciplinary decision-making in complex IBD care
- Understand how perspectives from gastroenterology, surgery and other disciplines contribute to individualized treatment plans
- Analyze disease phenotype and severity to guide management strategy
- Identify clinical, endoscopic, and radiologic markers that influence choice between escalating medical therapy and surgical options
- Explore communication strategies to involve families in shared decision-making, especially when weighing invasive options
- Learn key elements of pre-surgical optimization, nutritional support, and post-surgical monitoring for complications and recurrence
Gutsy Innovations: Optimizing Intestinal Failure Care
Moderators: David Galloway, MD, University of Alabama At Birmingham and Farhana Ali-Geiger, MD, University of Utah, Primary Children's Hospital
2:30 PM Intestinal Failure Associated Liver Disease: Strategies to Protect the Liver
Alexandra Carey, MD, Boston Children's Hospital
Learning objectives
- Describe the pathophysiology and risk factors contributing to the development of intestinal failure associated liver disease (IFALD) in pediatric patients
- Identify early subclinical/clinical signs and diagnostic strategies for detecting liver dysfunction in children with intestinal failure
- Evaluate current evidence-based strategies for protecting the liver and managing IFALD and its associated complications, including nutritional, pharmacologic, and surgical interventions
2:55 PM
NASPGHAN Foundation/Abbott Nutrition Advanced Fellowship Training in Pediatric Nutrition
Use of an In-Line Digestive Cartridge in Short Bowel Syndrome
Elaine Lin, MD, Children's Hospital of Philadelphia
3:07 PM Smart Records, Smarter Care for Intestinal Failure
Kerry Reed, MS, CPNP-PC, RN, Children’s Hospital Colorado and
Mary Abigail Garcia, MD, University of California, San Diego
Learning objectives:
- Demonstrate how electronic medical documentation can be standardized and streamlined
- Identify novel ways of obtaining data in a meaningful way to track patient characteristics, treatment and outcomes
3:32 PM AN INNOVATIVE DREAM PROMOTES INTESTINAL ADAPTATION AND PREVENTS
LIVER INJURY IN SHORT BOWEL SYNDROME
Shaurya Mehta, Saint Louis University School of Medicine
Advancing Pediatric GI Care: Research Abstracts Showcase
Moderators: Kathleen M. Loomes, MD, Children's Hospital of Philadelphia and Jennifer Woo Baidal, MD, MPH, Stanford University
2:30 PM
NASPGHAN Neurogratroenterology and Motility Prize – Basic
A LARGE-SCALE ELISA-BASED STUDY TO DETERMINE THE DIAGNOSTIC THRESHOLD
OF HUMAN PEPSIN A AS A BIOMARKER OF MICROASPIRATION
Nidhi Kapoor, PhD, Orlando Health
2:40 PM
NASPGHAN Award for Advancing Equity for Women in Medicine
THE CONTEXT DEPENDENT ROLE OF CELLULAR SENESCENCE IN BILIARY ATRESIA
Katie Conover, MD, University of Colorado
2:50 PM
Young Faculty Investigator Award
A NOVEL TRUNCATING EP300 MUTATION IMPAIRS INTESTINAL EPITHELIAL
DIFFERENTIATION IN PATIENT TISSUE AND ORGANOIDS AND CAN BE RESCUED BY
CHEMICAL HDAC INHIBITION
Lauren Collen, MD, Boston Children's Hospital
3:00 PM
Cyclic Vomiting Syndrome Association (CVSA) Young Investigator Prize in honor of B Li
IMPACT OF APREPITANT USE ON LENGTH OF STAY AND REPEAT HOSPITALIZATION
FOR CHILDREN WITH CYCLIC VOMITING SYNDROME
Sergio Cobos, MD, Nationwide Children's Hospital
3:10 PM
Feeding Matters Outstanding Pediatric Feeding Disorder Abstract Award
SALIVARY SUBSTANCE P IS A SENSITIVE AND SPECIFIC BIOMARKER OF
ASPIRATION IN INFANTS AND TODDLERS
Daniel Duncan, MD, Boston Children's Hospital
3:20 PM ENTEROCYTES REGULATE HEPATIC BILE ACID SYNTHESIS IN CO-CULTURED GUT AND
LIVER ORGANOIDS WITH INTERRUPTION UPON SIRNA TRANSFECTION
Ashlesha Bagwe, MD, Saint Louis University School of Medicine
3:30 PM DECODING CILIARY DYSFUNCTION IN HEPATOBILIARY DEVELOPMENT:
MECHANISTIC INSIGHTS INTO BILIARY ATRESIA PATHOGENESIS
Prasanna Venkatesh Ramachandran, MD, PhD, Boston Children's Hospital
3:40 PM Flash Abstracts
- CHILDREN WITH ANTRAL HYPOMOTILITY OR SMALL BOWEL DYSMOTILITY HAVE A GREATER RESPONSE TO GASTRIC ELECTRICAL STIMULATION
Eduardo Castillo Leon, MD, Nationwide Children's Hospital
- PEDIATRIC-SPECIFIC HIGH-RESOLUTION ESOPHAGEAL MANOMETRY PROTOCOLS ARE ESSENTIAL: EVIDENCE FROM A MULTICENTER COHORT STUDY
Trevor Davis, MD, Washington University School of Medicine
- GASTRIC PERORAL ENDOSCOPIC MYOTOMY (GPOEM) PERFORMED BY A PEDIATRIC GASTROENTEROLOGIST IS SAFE AND EFFECTIVE IN THE TREATMENT OF PEDIATRIC GASTROPARESIS
Ashley Croker-Benn, MPH, Boston Children's Hospital
Colonoscopy Skills Workshop*
Course Directors: Faith Ihekweazu, MD, Baylor College of Medicine and Catharine Walsh, MD, MEd, PhD, FRCPC, Hospital for Sick Children
4:15 PM – 6:00 PM Awards Ceremony