8:00 AM - 9:00 AM Module 1: Endoscopy
Moderators: Javier Monagas, MD, Baylor College of Medicine and Maria Oliva-Hemker, MD, Hopkins University School of Medicine

8:00 AM Foreign Body Ingestions
Petar Mamula, MD, Children's Hospital of Philadelphia
                     Learning objectives:

• Describe different types of foreign body ingestion in the pediatric population
• Discuss ingestion complications with an emphasis on magnets and lithium battery ingestions
• Review algorithms for treatment of various types of foreign body ingestions

8:20 AM Conquering GI strictures
Sabina Ahmed Mir, MD, University of North Carolina Chapel Hill
Learning objectives:

• Discuss the etiology of GI strictures in the pediatric population
• Review the appropriate diagnostic evaluation
• Describe the endoscopic approach to treatment

8:40 AM Polyps: To cut…Or to cut and run?
Brad Barth, MD, MPH, UT Southwestern and Children’s Medical Center Dallas
Learning objectives:

• Review the characteristics of high risk polyps
• Describe the most up to date interventions including cold snare polypectomy
• Discuss reasons to refer to expert centers for assistance

9:00 AM - 10:20 AM Module 2: Liver/Pancreas
Moderators: Ann Ming Yeh, MD, Stanford University and Toba Weinstein, MD, Children's Medical Center, Northwell Health

9:00 AM Evaluation of the jaundiced infant
Saul Karpen, MD, PhD, Emory University
Learning objectives:

• Describe the appropriate  evaluation of an infant with a direct bilirubin > 1.0 mg/dl at 48 hours of life
• Summarize the key components of the most recent joint NASPGHAN-ESPGHAN Guidelines on the Evaluation of the Cholestatic Infant, with incorporation of information and tools available since publication in 2017
• Develop a means to decide upon utilization of genetic testing and/or liver biopsy in your evaluation of the cholestatic infant
• Define the language common to genetic testing reports—benign, pathogenic, VOUS, etc…
• Describe the current status of the field regarding recently-approved anticholestatic therapies for Alagille Syndrome and PFICs

9:20 AM Managing the patient with acute pancreatitis: Beyond the basics
Aliye Uc, MD, University of Iowa Health Care
Learning objectives:

• Identify risk factors and predictors associated with pancreatitis disease severity
• Plan management of patients based on pancreatitis disease severity
• Assess potential pancreatitis complications and plan therapy

9:40 AM Imaging of the pancreas: Practical tips from you friendly radiologist
Andrew T. Trout, MD, Cincinnati Children's Hospital Medical Center
                     Learning objectives:

• Optimize selection of imaging for acute and chronic pancreatitis
• Define the relative benefits of US, CT and MRI for imaging of pancreatic disease
• Recognize the role of intravenous contrast material in imaging of pancreatic disease

10:00 AM Acute liver failure
James Squires, MD, MS, UPMC Children’s Hospital of Pittsburgh
                     Learning objectives:

• Recognize the clinical presentation and progression of pediatric acute liver failure
• Discuss an age-based diagnostic approach and clinical management of PALF
• Describe acute hepatitis outbreak and the future of PALF investigation

 
10:20 AM - 10:40 AM Break

10:40 AM - 12:00 PM Module 3: Inflammatory Diseases
Moderators: Riha Bhatt, MD, Vanderbilt Children's Hospital and Maria Oliva-Hemker, MD, Hopkins University School of Medicine

10:40 AM Oral small molecules in IBD 
Anne M. Griffiths, MD, FRCPC, Hospital for Sick Children
                     Learning objectives 

• Appreciate the pathways targeted by new oral small molecules in use or on the horizon for pediatric IBD
• Describe the efficacy and safety of Janus kinase (JAK) inhibitors and sphingosine-1-phosphate (S1P) receptor modulators in IBD
• Recognize how to recommend positioning of small molecules relative to biologics in Crohn’s disease and ulcerative colitis

11:00 AM Preventative Medicine  in the IBD patient
Sabina Ali, MD, UCSF Benioff Children's Hospital
                     Learning objectives:

• Review the literature and guidance on preventive health measures in inflammatory bowel disease (IBD)
• Review recommended immunizations for patients with IBD
• Identify how to integrate preventive screenings into practice to improve health outcomes in all patients with IBD

11:20 AM Managing the Child with VEO-IBD
Judith Kelsen, MD, Children's Hospital of Philadelphia
Learning objectives:

• Review the underlying disease drivers in VEO-IBD
• Describe the predominant phenotypes in children with VEO-IBD
• Review the comprehensive evaluation for children with VEO-IBD, including immune and genetic analyses
• Discuss the range of therapeutic options for children with VEO-IBD

11:40 AM Treat to Target in IBD
Jeremy Adler, MD, MSc, University of Michigan
Learning objectives:

• Review evidence for “treat to target” as a strategy for IBD
• Review evidence for specific treatment targets
• Review pediatric-specific evidence
• Identify a practical approach to treating to target for pediatric IBD

 
12:00 PM - 1:40 PM Lunch on your own

1:40 PM - 3:00 PM Module 4: Potpourri
Moderators: Alexander Koral, MD, Yale School of Medicine and Toba Weinstein, MD, Children's Medical Center, Northwell Health

1:40 PM COVID effects on the GI/hepatobiliary tract
Kara Gross Margolis, MD, New York University
Learning objectives:

• Describe the pathogenesis of COVID in the GI tract
• Identify the risk factors for COVID associated with specific GI diseases
• Recognize existing guidelines for those with COVID and underlying GI conditions

2:00 PM Calling a GI Consult: Growth & Nutrition Issues in NICU Infants
Timothy A. Sentongo, MD, University of Chicago
Learning objectives:

• Identify how to reliably predict mortality and prognosis in newborn and preterm infants
• Review manifestations, work up and differential diagnosis for GI disorders in the NICU patient
• Discuss management options for obvious and obscure GI disorders in newborn and preterm infants

2:20 PM Updates on the diagnosis and treatment of gluten related disorders
Maureen Leonard, MD, Massachusetts General Hospital
Learning objectives:

• Review updated diagnostic criteria for children with celiac disease
• Describe recommendations for management of children with gluten related disorders
• Recognize alternative treatment strategies in clinical development

2:40 PM What’s new for the use of PPIs 
Benjamin D. Gold, MD, FAAP, NASPGHAN-F, Gi Care for Kids, LLC
Learning objectives:

• Provide overview of the history behind development of proton pump inhibitors (PPIs) with a recognition of why improvements in acid suppression were needed. Point out when concerns about PPIs were raised, misuse and overuse
• Review gastroesophageal reflux (GER) in comparison to gastroesophageal reflux disease (GERD) in pediatrics. Phenotyping GERD; key for optimizing treatment of reflux disease
• Recognize why PPIs are key in the management of specific aerodigestive diseases
• Review the diagnosis of eosinophilic esophagitis and role of PPIs in treatment, moving away from PPI-REE and why EoE is important to understand in managing aerodigestive disease
• Review evidence-based guidelines for treatment of Helicobacter pylori (H. pylori) infection in children and importance of PPIs in treatment
• Describe the rationale for use of PPIs in NSAID associated gastro-duodenal inflammation and the role of acid suppression in gastrointestinal bleeding
• Evaluate future directions: promotility + acid suppression

3:00 PM - 4:00 PM Module 5: Disorders of the Brain-Gut Interaction/Motility
Moderators: Vrinda Bhardwaj, MD, Children's Hospital Los Angeles and Maria Oliva-Hemker, MD, Hopkins University School of Medicine

3:00 PM Esophageal motility disorders
Rachel Rosen, MD, Boston Children's Hospital
Learning objectives:

• Recognize the relationship between symptoms, dysmotility and functional disorders
• Describe new diagnostic tools to diagnose esophageal motor disorders
• Review the novel therapies available to treat esophageal motility disorders

3:20 PM Functional Nausea
Katja Kovacic, MD, Medical College of Wisconsin
Learning objectives: The learner will understand:

• Describe plausible mechanisms underlying chronic 'functional' nausea
• Identify diagnostic approaches
• Describe available therapeutic options

3:40 PM Constipation: The importance of having an evacuation plan
Carlo Di Lorenzo, MD, Nationwide Children's Hospital
Learning objectives:

• Discuss the testing needed in the evaluation of a child with severe constipation
• Illustrate when and how to use novel medications
• Explain the role of surgical interventions in the management of the child with intractable constipation