Friday, October 18
6:30 am – 8:00 am
Chicago VIII
Why Do We Need Dietary Therapy in Crohn’s Disease in an Era of Biologics?
Program Director: Robert N. Baldassano, MD
Colman Professor of Pediatrics, Children’s Hospital of Philadelphia
Why Do We Need Diet in an Era of Biologics?
Dr. Lindsey Albenberg
Children’s Hospital of Philadelphia, Philadelphia, PA
The need for alternatives to chronic immunosuppression as the prime treatment strategy in IBD is vital. Patients and families are concerned about drug safety and wish to manage their own IBD. Despite definite impact, the efficacy of current and novel biologics is limited in inducing and maintaining remission, and there are safety issues with long-term use. Given that gut luminal content is influenced by diet and drives inflammation, the evidence for therapeutic benefit with dietary therapy, and patients strong interest in dietary strategies, it is vital to include diet as part of the therapeutic strategy for IBD.
What Are the Targets for Dietary Therapy?
Dr. Arie Levine
Wolfson Medical Center, Tel Aviv, Israel
Recent evidence suggests that environmental factors and particularly diet may play a role in the pathogenesis of Crohn’s disease. Identification of these factors would open a window on to new therapeutic targets for treatment and prevention. By identifying plausible dietary components that negatively affect the microbiome, mucous layer and intestinal permeability; we were able to develop a novel well-tolerated diet that leads to equivalent remission rates, an identical decrease in inflammation and similar changes to the microbiome when compared with EEN in a randomized controlled trial.
Present State of the Art on Dietary Management in Crohn’s Disease
Dr. Eytan Wine
Edmonton Clinic Health Academy, Edmonton, Canada
There remains a gap between patient’s interest in diet in IBD and what we as health care providers can deliver. Exclusive enteral nutrition has been an exception to this, with good clinical data for induction of remission in pediatric Crohn’s disease, but recent studies offer exciting opportunities for innovation in dietary therapy.
The New Kid on the Block: The Crohn’s Disease Exclusion Diet for Induction of Remission
Rotem Sigall-Boneh, RD
Wolfson Medical Center, Tel Aviv, Israel
Diet has taken an important step forward with the adoption of EEN as a recommended first line therapy. This has led to a search for a more tolerable and feasible dietary approach for induction of remission. The existence of a novel dietary therapy comprised of a whole food diet coupled with 50% PEN will place diet and dietitians at the forefront of therapy of CD in the future.
Presented for attendees of the NASPGHAN Annual Meeting. This is not an official NASPGHAN event.
Financial support provided by Nestlé Health Science.
Nestlé Health Science is a Continuing Professional Education Accredited Provider with CDR, the credentialing agency for the Academy of Nutrition and Dietetics. Accredited provider number NE008. Nestlé Health Science is a Continuing Education Provider approved by the California Board of Registered Nursing; Provider Number 11366. 1.5 CPEUs available for dietitians and 1.5 contact hours available for nurses. There is no charge for participating in this program.